Jul 26, 2022 18:08
1 yr ago
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English term

staring model

English to Portuguese Science Genetics Vaccines
The terms appear in the following sentence:

"...ferritin was used as a staring model."

Discussion

Marjolein Snippe Jul 27, 2022:
starting model I have a suspicion that "staring model" should really be "starting model"; these can be used in the process of creating a molecular model of e.g. a protein or protein complex using electron microscopy. When I google, for example, "staring model" "molecular", a few scientific articles pop up.
I have checked two:
Automated cryo-EM structure refinement using correlation-driven molecular dynamics (by Maxim Igaev, Carsten Kutzner, Lars V. Bock, Andrea C. Vaiana , Helmut
Grubmüller)

and

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820213/

In both these, "staring model" occurs, but only as a typo for "starting model".

Proposed translations

+1
1 hr
Selected

modelo protagonista

Acredito que seja referente a algum protagonismo da ferritina.
Se você pudesse compartilhar uma parte maior do texto, seria mais fácil contextualizar.


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Note added at 8 horas (2022-07-27 02:27:33 GMT)
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Eu entendi que a Ferritina filtrada foi utilizada para ajudar a limpar a primeira imagem gerada 2D pela leitura do equipamento de forma que permitiu eliminar partículas sobrepostas para o refinamento em 3D. Parece que teve a função de um "branco" ou um auxiliar.

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Note added at 8 horas (2022-07-27 02:28:36 GMT)
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Como não consta o que está sendo analisado, não dá pra saber se a ferritina é um "branco" apenas, ou faz parte de algum outro processo mais complexo.
Example sentence:

ferritin was used as a staring model

Ferritina foi utilizada com um modelo protagonista

Note from asker:
Luciana, qui está a maior parte do parágrafo em que a expressão aparece: For cryo-electron microscopy analysis, particles were vitrified over holey carbon films using a Vitrobot Mark IV. Cryo-images of particles were collected on a Titan Krios electron microscope operated at liquid nitrogen temperatures and operated at 300 kV. Images were collected on a 4,096 × 4,096 charge-coupled-device (CCD) camera at a pixel size of 1.2 Å with defocus values ranging from approx. 2.8 to approx. 6 µm, and at doses ranging from approx. 10 to 20 e-/Å2. Particles were manually picked from images. Reference-free 2D classification indicated octahedral symmetry, which was imposed during 3D refinement. A smooth, spike less, low-pass filtered ferritin (PDB ID 2JD6) was used as a staring model. After removal of overlapping particles during the refinement process, the reconstruction (3D map) was calculated from 6,540 particles. All image analyses (2D and 3D) were carried out with the Relion package. Será que ajuda?
Muito obrigada Luciana. De acordo com o contexto global, para mim o que faz sentido é "protagonista".
Peer comment(s):

agree Ana Flávia Ribeiro
1 day 9 hrs
Something went wrong...
4 KudoZ points awarded for this answer.
+3
55 mins

modelo de observação

staring materials
materiais de observação

https://www.deepl.com/pt-BR/translator#en/pt/staring materia...

Chemical analysis of staring materials
https://www.researchgate.net/figure/Chemical-analysis-of-sta...
Peer comment(s):

agree Donatello Wilhelm
1 hr
Thanks Felipe!
agree Paulinho Fonseca
2 hrs
Thanks Paulinho!
agree Alaíde Assunção
1 day 5 hrs
Thanks Alaíde!
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