Glossary entry

English term or phrase:

Target on Cancer Cells

Chinese translation:

癌细胞上的特定靶点

Added to glossary by Xuling Wu
Sep 3, 2021 07:59
2 yrs ago
16 viewers *
English term

Target on Cancer Cells

English to Chinese Medical Medical (general)
Chimeric antigen receptor (CAR) T cell therapy, which uses engineered T cells to treat certain types of cancers, has often been a challenging approach to treating solid tumors. CAR T cells need to recognize a specific target on cancer cells to kill them. However, cancer cells do not always have the target, or they find ways to hide the target and stay invisible to CAR T cell attack.

Is "标靶" the correct translation for "target" in this paragraph? Please include citation of references in your answer. Thank you in advance.

Discussion

Xuling Wu (asker) Sep 3, 2021:
感谢 Frank 和 Randy 的指点。两位译友答案相同,这次 KudoZ points 给 Frank, 因为 Frank 的答案有详细的参考资料来源,帮助我对靶向和靶点两个概念多研究学习。
Xuling Wu (asker) Sep 3, 2021:
在这段话里,'target' 是作为名词使用的:"CAR T cells need to recognize a specific target on cancer cells to kill them." 如果是动词,'target' 就不需要介词 'on,' 直接说 'target the cencer cells" 就好了。‘癌细胞上面具体的靶向’?????

Proposed translations

34 mins
Selected

靶向癌细胞

在医学领域,target/targeting/targeted通常译作“靶向”,有动词和形容词的用法

比如 targeted therapy = 靶向治疗;targeted drug = 靶向药物

问题中“target cancer cell”,就是“靶向癌细胞”(动词用法)


--------------------------------------------------
Note added at 3 hrs (2021-09-03 11:39:32 GMT)
--------------------------------------------------

抱歉,之前手机上回复没看仔细……

如果作为名词,是“靶点”。a specific target on cancer cells = 癌细胞上的特定靶点

--------------------------------------------------
Note added at 3 hrs (2021-09-03 11:42:07 GMT)
--------------------------------------------------

几个ref:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000387/
https://zhuanlan.zhihu.com/p/56129165
https://www.bjcancer.org/Html/News/Articles/12254.html
Something went wrong...
4 KudoZ points awarded for this answer. Comment: "感谢 Frank 这样耐心、认真的解答。"
4 hrs

癌细胞上的具体靶点

target on cencer cells 是前面 recognize 的宾语,on cencer cells 是介词短语,作 target 的后置定语。
Something went wrong...
Term search
  • All of ProZ.com
  • Term search
  • Jobs
  • Forums
  • Multiple search