dysregulated terminal complement activation
French translation: activation dérégulée de la voie terminale du système du complément
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| 06:31 May 24, 2021 |
| English to French translations [PRO] Medical - Medical (general) / hémoglobinurie paroxystique nocturne | |||||||
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|  Selected response from: Bertrand Leduc United Kingdom Local time: 16:36 | ||||||
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| 4 +2 | activation dérégulée de la voie terminale du système du complément |
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Answers
16 mins confidence: 
peer agreement (net): +2
peer agreement (net): +2activation dérégulée de la voie terminale du système du complément Explanation: -------------------------------------------------- Note added at 17 minutes (2021-05-24 06:48:56 GMT) -------------------------------------------------- provoquée par une activation dérégulée de la voie alterne du système du complément. Le facteur H (FH) régule négativement la voie alterne du complément. https://www.chusj.org/fr/Labotest/Accueil/Analyses.aspx?IdAn... -------------------------------------------------- Note added at 18 minutes (2021-05-24 06:50:28 GMT) -------------------------------------------------- Cette voie terminale conduit à la formation du complexe d’attaque membranaire (CAM, C5b-9) et permet de lyser les pathogènes. Le système du complément est hautement régulé par des protéines sériques (C1inh, FI, C4BP, FH, clusterine, vitronectine) et membranaires (CR1, MCP, DAF, CD59). https://www.ipubli.inserm.fr/bitstream/handle/10608/9640/MS_... |
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