mechanism of action and resistance biomarkers
| 13:29 Oct 26, 2014 |
| English language (monolingual) [PRO] Medical - Medical (general) | |||||
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| 5 +1 | mechanism of action and resistance biomarkers |
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| 3 -1 | mechanism of action and [mechanism of] resistance biomarkers |
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| findings |
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| Discussion entries: 1 | |
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Answers
4 hrs confidence: 
peer agreement (net): -1
peer agreement (net): -1mechanism of action and [mechanism of] resistance biomarkers Explanation: Biomarker a naturally occurring molecule, gene, or characteristic by which a particular pathological or physiological process, disease, etc. can be identified. The statement should be read as: "mechanism of action and [mechanism of] resistance biomarkers." THis is similar to the earlier text, "mechanism of action biomarkers." I do not think there is an "of" missing. Seems okay to me. |
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10 hrs confidence: peer agreement (net): +1
peer agreement (net): +1mechanism of action and resistance biomarkers Explanation: The substudy will investigate three issues: - pharmacodynamics (of the study drug in question) - - mechanism of action (of the study drug in question) - biomarkers of resistance (to the study drug in question) |
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Reference comments
1 hr peer agreement (net): +3 |
| Reference: findings Reference information: "resistance biomarkers" and biomarkers of resistance" both seem to be used -------------------------------------------------- Note added at 1 hr (2014-10-26 14:42:15 GMT) -------------------------------------------------- mechanism of action stands alone as a phrase not sure what your problem is here? -------------------------------------------------- Note added at 1 hr (2014-10-26 14:44:01 GMT) -------------------------------------------------- Novel biomarkers: neuroInflammation www.neuroinflammation.eu/projects/novel-biomarkers.html Stroke and MS are complex diseases with several mechanisms contributing ... biomarkers can provide insight into the mechanism of action of a drug and could ... -------------------------------------------------- Note added at 1 hr (2014-10-26 14:54:54 GMT) -------------------------------------------------- I am unable to find much with biomarkers mechanism of action/biomarker mechanism of action The biomarkers are used to reflect the mechanism of action of the drug... Biomarkers of Histone Deacetylase Inhibitor Activity in a ... broker.edina.ac.uk/294189/1/PMC3934935.pdf by AH Ree - 2014 - Related articles 25 Feb 2014 - ***An optimum biological dose may be the dose that is associated with pharmacodynamic biomarkers reflecting the mechanism of drug action***. -------------------------------------------------- Note added at 2 hrs (2014-10-26 16:09:38 GMT) -------------------------------------------------- personally, I think the text is poorly written If I were you I would find a good bona fide English article on the subject and compare. |
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